University of Groningen Synthesis of Optically Active beta- or gamma-Alkyl-Substituted Alcohols through Copper-Catalyzed Asymmetric Allylic Alkylation with Organolithium Reagents
نویسندگان
چکیده
An efficient one-pot synthesis of optically active β-alkyl-substituted alcohols through a tandem coppercatalyzed asymmetric allylic alkylation (AAA) with organolithium reagents and reductive ozonolysis is presented. Furthermore, hydroboration−oxidation following the Cucatalyzed AAA leads to the corresponding homochiral γalkyl-substituted alcohols.
منابع مشابه
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